FFCD-1004 Clinical Trial: Impact of Cytidine Deaminase Activity on Clinical Outcome in Gemcitabine-Monotherapy Treated Patients

PURPOSE: Because cytidine deaminase (CDA) is the key enzyme in gemcitabine metabolism, numerous studies have attempted to investigate impact of CDA status (i.e. genotype or phenotype) on clinical outcome. To date, data are still controversial because none of these studies has fully investigated geno...

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Detalles Bibliográficos
Autores principales: Serdjebi, Cindy, Gagnière, Johan, Desramé, Jérôme, Fein, Francine, Guimbaud, Rosine, François, Eric, André, Thierry, Seitz, Jean-François, Montérymard, Carole, Arsene, Dominique, Volet, Julien, Abakar-Mahamat, Abakar, Lecomte, Thierry, Guerin-Meyer, Véronique, Legoux, Jean-Louis, Deplanque, Gaël, Guillet, Pierre, Ciccolini, Joseph, Lepage, Côme, Dahan, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550302/
https://www.ncbi.nlm.nih.gov/pubmed/26308942
http://dx.doi.org/10.1371/journal.pone.0135907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550302/
https://www.ncbi.nlm.nih.gov/pubmed/26308942
http://dx.doi.org/10.1371/journal.pone.0135907

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