Self-Assembly of Aβ40, Aβ42 and Aβ43 Peptides in Aqueous Mixtures of Fluorinated Alcohols

Fluorinated alcohols such as hexafluoroisopropanol (HFIP) and trifluoroethanol (TFE) have the ability to promote α-helix and β-hairpin structure in proteins and peptides. HFIP has been used extensively to dissolve various amyloidogenic proteins and peptides including Aβ, in order to ensure their mon...

Descripción completa

Detalles Bibliográficos
Autores principales: Pachahara, Sanjai Kumar, Adicherla, Harikrishna, Nagaraj, Ramakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550328/
https://www.ncbi.nlm.nih.gov/pubmed/26308214
http://dx.doi.org/10.1371/journal.pone.0136567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550328/
https://www.ncbi.nlm.nih.gov/pubmed/26308214
http://dx.doi.org/10.1371/journal.pone.0136567

Ejemplares similares