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Vasomotor Reaction to Cyclooxygenase-1-Mediated Prostacyclin Synthesis in Carotid Arteries from Two-Kidney-One-Clip Hypertensive Mice
This study tested the hypothesis that in hypertensive arteries cyclooxygenase-1 (COX-1) remains as a major form, mediating prostacyclin (prostaglandin I(2); PGI(2)) synthesis that may evoke a vasoconstrictor response in the presence of functional vasodilator PGI(2) (IP) receptors. Two-kidney-one-cli...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550394/ https://www.ncbi.nlm.nih.gov/pubmed/26308616 http://dx.doi.org/10.1371/journal.pone.0136738 |