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Vasomotor Reaction to Cyclooxygenase-1-Mediated Prostacyclin Synthesis in Carotid Arteries from Two-Kidney-One-Clip Hypertensive Mice

This study tested the hypothesis that in hypertensive arteries cyclooxygenase-1 (COX-1) remains as a major form, mediating prostacyclin (prostaglandin I(2); PGI(2)) synthesis that may evoke a vasoconstrictor response in the presence of functional vasodilator PGI(2) (IP) receptors. Two-kidney-one-cli...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Li, Zhenhua, Zhang, Yingzhan, Luo, Wenhong, Zhang, Jiling, Li, Hui, Zhou, Yingbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550394/
https://www.ncbi.nlm.nih.gov/pubmed/26308616
http://dx.doi.org/10.1371/journal.pone.0136738