Generation of Monoclonal Antibodies against Dengue Virus Type 4 and Identification of Enhancing Epitopes on Envelope Protein

The four serotypes of dengue virus (DENV1-4) pose a serious threat to global health. Cross-reactive and non-neutralizing antibodies enhance viral infection, thereby exacerbating the disease via antibody-dependent enhancement (ADE). Studying the epitopes targeted by these enhancing antibodies would i...

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Detalles Bibliográficos
Autores principales: Tang, Chung-Tao, Liao, Mei-Ying, Chiu, Chien-Yu, Shen, Wen-Fan, Chiu, Chiung-Yi, Cheng, Ping-Chang, Chang, Gwong-Jen J., Wu, Han-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550467/
https://www.ncbi.nlm.nih.gov/pubmed/26309127
http://dx.doi.org/10.1371/journal.pone.0136328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550467/
https://www.ncbi.nlm.nih.gov/pubmed/26309127
http://dx.doi.org/10.1371/journal.pone.0136328

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