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Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites

Metronidazole has been used clinically for over 50 years as an antiparasitic and broad-spectrum antibacterial agent effective against anaerobic bacteria. However resistance to metronidazole in parasites and bacteria has been reported, and improved second-generation metronidazole analogues are needed...

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Detalles Bibliográficos
Autores principales:	Jarrad, Angie M., Karoli, Tomislav, Debnath, Anjan, Tay, Chin Yen, Huang, Johnny X., Kaeslin, Geraldine, Elliott, Alysha G., Miyamoto, Yukiko, Ramu, Soumya, Kavanagh, Angela M., Zuegg, Johannes, Eckmann, Lars, Blaskovich, Mark A.T., Cooper, Matthew A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editions Scientifiques Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550478/ https://www.ncbi.nlm.nih.gov/pubmed/26117821 http://dx.doi.org/10.1016/j.ejmech.2015.06.019

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