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Optimization of optical and mechanical properties of real architecture for 3-dimensional tissue equivalents: Towards treatment of limbal epithelial stem cell deficiency

Limbal epithelial stem cell (LESC) deficiency can cause blindness. Transplantation of cultured human limbal epithelial cells (hLE) on human amniotic membrane (HAM) can restore vision but clinical graft manufacture can be unreliable. We have developed a reliable and robust tissue equivalent (TE) alte...

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Detalles Bibliográficos
Autores principales: Massie, Isobel, Kureshi, Alvena K., Schrader, Stefan, Shortt, Alex J., Daniels, Julie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550494/
https://www.ncbi.nlm.nih.gov/pubmed/26092352
http://dx.doi.org/10.1016/j.actbio.2015.06.007

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