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Early adversity disrupts the adult use of aversive prediction errors to reduce fear in uncertainty

Early life adversity increases anxiety in adult rodents and primates, and increases the risk for developing post-traumatic disorder (PTSD) in humans. We hypothesized that early adversity impairs the use of learning signals -negative, aversive prediction errors–to reduce fear in uncertainty. To test...

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Detalles Bibliográficos
Autores principales: Wright, Kristina M., DiLeo, Alyssa, McDannald, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550796/
https://www.ncbi.nlm.nih.gov/pubmed/26379520
http://dx.doi.org/10.3389/fnbeh.2015.00227