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Early adversity disrupts the adult use of aversive prediction errors to reduce fear in uncertainty
Early life adversity increases anxiety in adult rodents and primates, and increases the risk for developing post-traumatic disorder (PTSD) in humans. We hypothesized that early adversity impairs the use of learning signals -negative, aversive prediction errors–to reduce fear in uncertainty. To test...
Autores principales: | Wright, Kristina M., DiLeo, Alyssa, McDannald, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550796/ https://www.ncbi.nlm.nih.gov/pubmed/26379520 http://dx.doi.org/10.3389/fnbeh.2015.00227 |
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