Plaque-associated lipids in Alzheimer’s diseased brain tissue visualized by nonlinear microscopy

By simultaneous coherent anti-Stokes Raman scattering (CARS) and 2-photon fluorescence microscopy of Thioflavin-S stained Alzheimer´s diseased human brain tissues, we show evidence of lipid deposits co-localizing with fibrillar β-amyloid (Aβ) plaques. Two lipid morphologies can be observed; lamellar...

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Detalles Bibliográficos
Autores principales: Kiskis, Juris, Fink, Helen, Nyberg, Lena, Thyr, Jacob, Li, Jia-Yi, Enejder, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550829/
https://www.ncbi.nlm.nih.gov/pubmed/26311128
http://dx.doi.org/10.1038/srep13489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550829/
https://www.ncbi.nlm.nih.gov/pubmed/26311128
http://dx.doi.org/10.1038/srep13489

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