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Allele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism
The major histocompatibility complex class I chain-related gene A (MICA) is involved in immune responses of both nature killer (NK) cells and subsets of T cells with its receptor NKG2D. MICA is highly polymorphic in sequence which leads to MICA protein variants with distinct features. Specific polym...
Autores principales: | Shi, Chunhua, Li, Hongye, Couturier, Jacob P, Yang, Karen, Guo, Xinjian, He, Dongyi, Lewis, Dorothy E, Zhou, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550945/ https://www.ncbi.nlm.nih.gov/pubmed/26322142 http://dx.doi.org/10.2174/1874312901409010060 |
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