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The Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers

[Image: see text] Liver phenylalanine hydroxylase is allosterically activated by phenylalanine. The structural changes that accompany activation have not been identified, but recent studies of the effects of phenylalanine on the isolated regulatory domain of the enzyme support a model in which pheny...

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Detalles Bibliográficos
Autores principales:	Zhang, Shengnan, Hinck, Andrew P., Fitzpatrick, Paul F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551101/ https://www.ncbi.nlm.nih.gov/pubmed/26252467 http://dx.doi.org/10.1021/acs.biochem.5b00616

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