Cargando…

Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

Cardiolipin (CL) is an atypical, dimeric phospholipid essential for mitochondrial dynamics in eukaryotic cells. Dynamin-related protein 1 (Drp1), a cytosolic member of the dynamin superfamily of large GTPases, interacts with CL and functions to sustain the balance of mitochondrial division and fusio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stepanyants, Natalia, Macdonald, Patrick J., Francy, Christopher A., Mears, Jason A., Qi, Xin, Ramachandran, Rajesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551322/ https://www.ncbi.nlm.nih.gov/pubmed/26157169 http://dx.doi.org/10.1091/mbc.E15-06-0330

Ejemplares similares

Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission
por: Lu, Bin, et al.
Publicado: (2018)

A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission
por: Macdonald, Patrick J., et al.
Publicado: (2014)

GFP fluorescence tagging alters dynamin-related protein 1 oligomerization dynamics and creates disassembly-refractory puncta to mediate mitochondrial fission
por: Montecinos-Franjola, Felipe, et al.
Publicado: (2020)

Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission
por: Mehrotra, Niharika, et al.
Publicado: (2014)

Dynamin in fission and fusion
por: LeBrasseur, Nicole
Publicado: (2004)

Structure of a mitochondrial fission dynamin in the closed conformation
por: Bohuszewicz, Olga, et al.
Publicado: (2018)

Allosteric control of dynamin-related protein 1-catalyzed mitochondrial fission through a conserved disordered C-terminal Short Linear Motif
por: Pérez-Jover, Isabel, et al.
Publicado: (2023)

Cardiolipin targets a dynamin-related protein to the nuclear membrane
por: Kar, Usha Pallabi, et al.
Publicado: (2021)

Dynamin Rings: Not Just for Fission
por: Sever, Sanja, et al.
Publicado: (2013)

Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer
por: Francy, Christopher A., et al.
Publicado: (2017)

Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1
por: Bustillo-Zabalbeitia, Itsasne, et al.
Publicado: (2014)

Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes
por: Koirala, Sajjan, et al.
Publicado: (2010)

A unique dynamin-related protein is essential for mitochondrial fission in Toxoplasma gondii
por: Melatti, Carmen, et al.
Publicado: (2019)

Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity
por: Manczak, Maria, et al.
Publicado: (2019)

Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo
por: Kornfeld, Opher S., et al.
Publicado: (2018)

Corrigendum: Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity
por: Manczak, Maria, et al.
Publicado: (2019)

Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation
por: Yamamori, Tohru, et al.
Publicado: (2015)

Geometric instability catalyzes mitochondrial fission
por: Irajizad, Ehsan, et al.
Publicado: (2019)

Structural inhibition of dynamin-mediated membrane fission by endophilin
por: Hohendahl, Annika, et al.
Publicado: (2017)

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission
por: Richter, Viviane, et al.
Publicado: (2014)

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
por: Ji, Wei-ke, et al.
Publicado: (2015)

Squamosamide Derivative FLZ Diminishes Aberrant Mitochondrial Fission by Inhibiting Dynamin-Related Protein 1
por: Yang, Hanyu, et al.
Publicado: (2021)

Impact of Antioxidants on Cardiolipin Oxidation in Liposomes: Why Mitochondrial Cardiolipin Serves as an Apoptotic Signal?
por: Lokhmatikov, Alexey V., et al.
Publicado: (2016)

Dynamin-Catalyzed Membrane Fission Requires Coordinated GTP Hydrolysis
por: Liu, Ya-Wen, et al.
Publicado: (2013)

The pleckstrin-homology domain of dynamin is dispensable for membrane constriction and fission
por: Dar, Srishti, et al.
Publicado: (2017)

The role of scaffold reshaping and disassembly in dynamin driven membrane fission
por: Pannuzzo, Martina, et al.
Publicado: (2018)

Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission
por: Kamerkar, Sukrut C., et al.
Publicado: (2018)

Mechanistic Issues of the Interaction of the Hairpin-Forming Domain of tBid with Mitochondrial Cardiolipin
por: Gonzalvez, François, et al.
Publicado: (2010)

Physiological and Pathological Significance of Dynamin-Related Protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System
por: Cho, Bongki, et al.
Publicado: (2013)

Mycobacterial dynamin-like protein IniA mediates membrane fission
por: Wang, Manfu, et al.
Publicado: (2019)

Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins
por: Kalia, Raghav, et al.
Publicado: (2019)

Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium
por: Oh, Phil, et al.
Publicado: (1998)

Molecular structural diversity of mitochondrial cardiolipins
por: Oemer, Gregor, et al.
Publicado: (2018)

Role of Cardiolipin in Mitochondrial Signaling Pathways
por: Dudek, Jan
Publicado: (2017)

The Role of Mitochondrial Dynamin in Stroke
por: Li, Chenchen, et al.
Publicado: (2022)

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway
por: Li, Jincheng, et al.
Publicado: (2010)

Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission
por: Sarin, M, et al.
Publicado: (2013)

Membrane fission by dynamin: what we know and what we need to know
por: Antonny, Bruno, et al.
Publicado: (2016)

Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein
por: Ryan, Tammy, et al.
Publicado: (2018)

Cardiolipin, the Mitochondrial Signature Lipid: Implication in Cancer
por: Ahmadpour, Seyedeh Tayebeh, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3ooohc2gopr1n9o9ikovmifvmn