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Methylprednisolone attenuates lipopolysaccharide-induced Fractalkine expression in kidney of Lupus-prone MRL/lpr mice through the NF-kappaB pathway

BACKGROUND: Fractalkine (FKN) is involved in the occurrence and development of human lupus nephritis. It is known to be upregulated by lipopolysaccharide (LPS) as a stimulus in vivo. MRL/lpr mice have been used as an in vivo model to study lupus nephritis. Methylprednisolone (MP) is used widely in t...

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Detalles Bibliográficos
Autores principales:	You, Yanwu, Qin, Yueqiu, Lin, Xu, Yang, Fafen, Li, Jun, Sooranna, Suren R., Pinhu, Liao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551515/ https://www.ncbi.nlm.nih.gov/pubmed/26310926 http://dx.doi.org/10.1186/s12882-015-0145-y

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