Cargando…

Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles

INTRODUCTION: Alzheimer’s disease (AD) is associated with neurofibrillary pathology, including neurofibrillary tangles (NFT), neuritic plaques (NP) and neuropil threads containing aggregated microtubule associated protein tau. Aggregated tau is also associated with granulovacuolar degeneration (GVD)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hunter, Sally, Minett, Thais, Polvikoski, Tuomo, Mukaetova-Ladinska, Elizabeta, Brayne, Carol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551529/ https://www.ncbi.nlm.nih.gov/pubmed/26315613 http://dx.doi.org/10.1186/s13195-015-0141-2

Ejemplares similares

The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer’s disease
por: Hondius, David C., et al.
Publicado: (2021)

Phosphatidylinositol-4,5-bisphosphate is enriched in granulovacuolar degeneration bodies and neurofibrillary tangles
por: Nishikawa, Tomokazu, et al.
Publicado: (2014)

Aluminum and Tau in Neurofibrillary Tangles in Familial Alzheimer’s Disease
por: Mold, Matthew John, et al.
Publicado: (2021)

Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles
por: Dregni, Aurelio J., et al.
Publicado: (2022)

NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain
por: Fadul, Motaz M., et al.
Publicado: (2020)

Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease
por: Ono, Masahiro, et al.
Publicado: (2016)

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice
por: Jaworski, Tomasz, et al.
Publicado: (2009)

Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease
por: Miyashita, A, et al.
Publicado: (2014)

Neurofibrillary tangles in Alzheimer's disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics
por: Metaxas, Athanasios, et al.
Publicado: (2016)

Granulovacuolar degeneration bodies: red alert for neurons with MAPT/tau pathology
por: Wiersma, Vera I., et al.
Publicado: (2019)

Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology
por: Jorge-Oliva, Marta, et al.
Publicado: (2022)

Human TAU(P301L) overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain
por: Cosacak, Mehmet I., et al.
Publicado: (2017)

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease
por: Bryan, Kathryn J, et al.
Publicado: (2008)

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer’s disease
por: Wang, Chunyu, et al.
Publicado: (2016)

In vivo quantification of neurofibrillary tangles with [(18)F]MK-6240
por: Pascoal, Tharick A., et al.
Publicado: (2018)

Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology
por: Hou, Xu, et al.
Publicado: (2020)

Hippocampal sclerosis, hippocampal neuron loss patterns and TDP‐43 in the aged population
por: Hokkanen, Suvi R. K., et al.
Publicado: (2017)

Intraneuronal Aβ immunoreactivity is not a predictor of brain amyloidosis-β or neurofibrillary degeneration
por: Wegiel, Jerzy, et al.
Publicado: (2007)

Granulovacuolar Degenerations Appear in Relation to Hippocampal Phosphorylated Tau Accumulation in Various Neurodegenerative Disorders
por: Yamazaki, Yuu, et al.
Publicado: (2011)

Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology
por: Wiersma, Vera I., et al.
Publicado: (2019)

Clinical Neuropathology image 5-2016: neurofibrillary tangle-rich ganglioglioma
por: Gelpi, Ellen, et al.
Publicado: (2016)

Braak neurofibrillary tangle staging prediction from in vivo MRI metrics
por: Dallaire-Théroux, Caroline, et al.
Publicado: (2019)

Association of Neighborhood-Level Disadvantage With Neurofibrillary Tangles on Neuropathological Tissue Assessment
por: Powell, W. Ryan, et al.
Publicado: (2022)

Granulovacuolar Degeneration in Brains of Senile Cynomolgus Monkeys
por: Darusman, Huda S., et al.
Publicado: (2019)

Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands
por: Rafique, Waqas, et al.
Publicado: (2018)

Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease
por: Bengoa-Vergniory, Nora, et al.
Publicado: (2021)

CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles
por: Kaeser, Stephan A., et al.
Publicado: (2021)

Early amygdala and ERC atrophy linked to 3D reconstruction of rostral neurofibrillary tau tangle pathology in Alzheimer’s disease()
por: Stouffer, Kaitlin M., et al.
Publicado: (2023)

Current and Future Perspectives of Liaison Psychiatry Services: Relevance for Older People’s Care
por: Mukaetova-Ladinska, Elizabeta B.
Publicado: (2016)

Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain
por: Cox, Paul Alan, et al.
Publicado: (2016)

Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies
por: Chibnik, Lori B, et al.
Publicado: (2017)

Entorhinal Subfield Vulnerability to Neurofibrillary Tangles in Aging and the Preclinical Stage of Alzheimer’s Disease
por: Llamas-Rodríguez, Josué, et al.
Publicado: (2022)

Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment
por: Marx, Gabriel A., et al.
Publicado: (2022)

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
por: Ahmed, Zeshan, et al.
Publicado: (2014)

Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles
por: Qi, Yao, et al.
Publicado: (2020)

Molecular Markers for Granulovacuolar Degeneration Are Present in Rimmed Vacuoles
por: Nakamori, Masahiro, et al.
Publicado: (2013)

Granulovacuolar Degeneration in Hippocampus of Neurodegenerative Diseases: Quantitative Study
por: Kurdi, Maher, et al.
Publicado: (2016)

MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies
por: Lund, Harald, et al.
Publicado: (2014)

Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D
por: Ando, Kunie, et al.
Publicado: (2014)

Aluminum and Neurofibrillary Tangle Co-Localization in Familial Alzheimer’s Disease and Related Neurological Disorders
por: Mold, Matthew John, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mp6o0a18muorq3ld9bsjkgniqd