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Erythropoietin Attenuates Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension through Interplay between Endothelial Progenitor Cells and Heme Oxygenase
BACKGROUND: Pulmonary arterial hypertension (PAH) is a pulmonary vascular disease with a high mortality, characterized by typical angio-proliferative lesions. Erythropoietin (EPO) attenuates pulmonary vascular remodeling in PAH. We postulated that EPO acts through mobilization of endothelial progeni...
Autores principales: | van Loon, Rosa Laura E., Bartelds, Beatrijs, Wagener, Frank A. D. T. G., Affara, Nada, Mohaupt, Saffloer, Wijnberg, Hans, Pennings, Sebastiaan W. C., Takens, Janny, Berger, Rolf M. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551834/ https://www.ncbi.nlm.nih.gov/pubmed/26380246 http://dx.doi.org/10.3389/fped.2015.00071 |
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