Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging

Data on biological mechanisms of aging are mostly obtained from cross-sectional study designs. An inherent disadvantage of this design is that inter-individual differences can mask small but biologically significant age-dependent changes. A serially sampled design (same individual at different time...

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Detalles Bibliográficos
Autores principales: Jung, Marc, Jin, Seung-Gi, Zhang, Xiaoying, Xiong, Wenying, Gogoshin, Grigoriy, Rodin, Andrei S., Pfeifer, Gerd P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551908/
https://www.ncbi.nlm.nih.gov/pubmed/25977295
http://dx.doi.org/10.1093/nar/gkv473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551908/
https://www.ncbi.nlm.nih.gov/pubmed/25977295
http://dx.doi.org/10.1093/nar/gkv473

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