Mediator tail subunits can form amyloid-like aggregates in vivo and affect stress response in yeast

The Med2, Med3 and Med15 proteins form a heterotrimeric subdomain in the budding yeast Mediator complex. This Med15 module is an important target for many gene specific transcription activators. A previous proteome wide screen in yeast identified Med3 as a protein with priogenic potential. In the pr...

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Detalles Bibliográficos
Autores principales: Zhu, Xuefeng, Chen, Lihua, Carlsten, Jonas O. P., Liu, Qian, Yang, Junsheng, Liu, Beidong, Gustafsson, Claes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551914/
https://www.ncbi.nlm.nih.gov/pubmed/26138482
http://dx.doi.org/10.1093/nar/gkv629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551914/
https://www.ncbi.nlm.nih.gov/pubmed/26138482
http://dx.doi.org/10.1093/nar/gkv629

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