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Structural heterogeneity and functional diversity of topologically associating domains in mammalian genomes

Recent chromosome conformation capture (3C) derived techniques have revealed that topologically associating domain (TAD) is a pervasive element in chromatin three-dimensional (3D) organization. However, there is currently no parameter to quantitatively measure the structural characteristics of TADs,...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Tao, Dong, Peng-Fei, Zhang, Hong-Yu, Peng, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551926/
https://www.ncbi.nlm.nih.gov/pubmed/26150425
http://dx.doi.org/10.1093/nar/gkv684