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Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides

Toxin-antitoxin (TA) systems play important roles in bacterial physiology, such as multidrug tolerance, biofilm formation, and arrest of cellular growth under stress conditions. To develop novel antimicrobial agents against tuberculosis, we focused on VapBC systems, which encompass more than half of...

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Detalles Bibliográficos
Autores principales:	Lee, In-Gyun, Lee, Sang Jae, Chae, Susanna, Lee, Ki-Young, Kim, Ji-Hun, Lee, Bong-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551927/ https://www.ncbi.nlm.nih.gov/pubmed/26150422 http://dx.doi.org/10.1093/nar/gkv689

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