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RNA aptamer inhibitors of a restriction endonuclease

Restriction endonucleases (REases) recognize and cleave short palindromic DNA sequences, protecting bacterial cells against bacteriophage infection by attacking foreign DNA. We are interested in the potential of folded RNA to mimic DNA, a concept that might be applied to inhibition of DNA-binding pr...

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Detalles Bibliográficos
Autores principales: Mondragón, Estefanía, Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551934/
https://www.ncbi.nlm.nih.gov/pubmed/26184872
http://dx.doi.org/10.1093/nar/gkv702