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On the availability of microRNA-induced silencing complexes, saturation of microRNA-binding sites and stoichiometry
Several authors have suggested or inferred that modest changes in microRNA expression can potentiate or impinge on their capacity to mediate gene repression, and that doing so could play a significant role in diseases. Such interpretations are based on several assumptions, namely: (i) changes in mic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551941/ https://www.ncbi.nlm.nih.gov/pubmed/26227970 http://dx.doi.org/10.1093/nar/gkv720 |