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Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency

The transcription factors OCT4 and SOX2 are required for generating induced pluripotent stem cells (iPSCs) and for maintaining embryonic stem cells (ESCs). OCT4 and SOX2 associate and bind to DNA in different configurations depending on the arrangement of their individual DNA binding elements. Here...

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Detalles Bibliográficos
Autores principales:	Tapia, Natalia, MacCarthy, Caitlin, Esch, Daniel, Gabriele Marthaler, Adele, Tiemann, Ulf, Araúzo-Bravo, Marcos J., Jauch, Ralf, Cojocaru, Vlad, Schöler, Hans R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551974/ https://www.ncbi.nlm.nih.gov/pubmed/26314899 http://dx.doi.org/10.1038/srep13533

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