Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

Hippocampal pathology is likely to contribute to cognitive disability in Down syndrome (DS), yet the neural network basis of this pathology and its contributions to different facets of cognitive impairment remain unclear. Here, we report dysfunctional connectivity between dentate gyrus (DG) and CA3...

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Detalles Bibliográficos
Autores principales: Witton, J., Padmashri, R., Zinyuk, L.E., Popov, V.I., Kraev, I., Line, S.J., Jensen, T.P., Tedoldi, A., Cummings, D.M., Tybulewicz, V.L.J., Fisher, E.M.C., Bannerman, D.M., Randall, A.D., Brown, J.T., Edwards, F.A., Rusakov, D.A., Stewart, M.G., Jones, M.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552261/
https://www.ncbi.nlm.nih.gov/pubmed/26237367
http://dx.doi.org/10.1038/nn.4072

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