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High-Throughput All-Optical Analysis of Synaptic Transmission and Synaptic Vesicle Recycling in Caenorhabditis elegans

Synaptic vesicles (SVs) undergo a cycle of biogenesis and membrane fusion to release transmitter, followed by recycling. How exocytosis and endocytosis are coupled is intensively investigated. We describe an all-optical method for identification of neurotransmission genes that can directly distingui...

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Detalles Bibliográficos
Autores principales: Wabnig, Sebastian, Liewald, Jana Fiona, Yu, Szi-chieh, Gottschalk, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552474/
https://www.ncbi.nlm.nih.gov/pubmed/26312752
http://dx.doi.org/10.1371/journal.pone.0135584