Renoprotective effects of combined SGLT2 and ACE inhibitor therapy in diabetic Dahl S rats

This study examined whether control of hyperglycemia with a new SGLT2 inhibitor, luseogliflozin, given alone or in combination with lisinopril could prevent the development of renal injury in diabetic Dahl salt-sensitive (Dahl S) rats treated with streptozotocin (Dahl-STZ). Blood glucose levels incr...

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Detalles Bibliográficos
Autores principales: Kojima, Naoki, Williams, Jan M, Slaughter, Tiffani N, Kato, Sota, Takahashi, Teisuke, Miyata, Noriyuki, Roman, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552522/
https://www.ncbi.nlm.nih.gov/pubmed/26169541
http://dx.doi.org/10.14814/phy2.12436

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