Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis

Deregulated expression of activin A is reported in several tumors, but its biological functions in oral squamous cell carcinoma (OSCC) are unknown. Here, we investigate whether activin A can play a causal role in OSCCs. Activin A expression was assessed by qPCR and immunohistochemistry in OSCC tissu...

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Detalles Bibliográficos
Autores principales: Bufalino, Andreia, Cervigne, Nilva K., de Oliveira, Carine Ervolino, Fonseca, Felipe Paiva, Rodrigues, Priscila Campioni, Macedo, Carolina Carneiro Soares, Sobral, Lays Martin, Miguel, Marcia Costa, Lopes, Marcio Ajudarte, Leme, Adriana Franco Paes, Lambert, Daniel W., Salo, Tuula A., Kowalski, Luiz Paulo, Graner, Edgard, Coletta, Ricardo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552554/
https://www.ncbi.nlm.nih.gov/pubmed/26317418
http://dx.doi.org/10.1371/journal.pone.0136599

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