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Identifying a Neuromedin U Receptor 2 Splice Variant and Determining Its Roles in the Regulation of Signaling and Tumorigenesis In Vitro

Neuromedin U (NMU) activates two G protein-coupled receptors, NMUR1 and NMUR2; this signaling not only controls many physiological responses but also promotes tumorigenesis in diverse tissues. We recently identified a novel truncated NMUR2 derived by alternative splicing, namely NMUR2S, from human o...

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Detalles Bibliográficos
Autores principales: Lin, Ting-Yu, Huang, Wei-Lin, Lee, Wei-Yu, Luo, Ching-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552561/
https://www.ncbi.nlm.nih.gov/pubmed/26317338
http://dx.doi.org/10.1371/journal.pone.0136836