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Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis

Childhood acute lymphoblastic leukemia (ALL) blasts are characterized by inhibited apoptosis promoting fast disease progress. It is known that in chronic lymphocytic and acute myeloid leukemias the reduced apoptosis is strongly related with the activity of calpain-calpastatin system (CCS) composed o...

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Detalles Bibliográficos
Autores principales:	Mikosik, Anna, Henc, Izabella, Ruckemann-Dziurdzińska, Katarzyna, Frąckowiak, Joanna E., Płoszyńska, Anna, Balcerska, Anna, Bryl, Ewa, Witkowski, Jacek M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552652/ https://www.ncbi.nlm.nih.gov/pubmed/26317226 http://dx.doi.org/10.1371/journal.pone.0136615

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