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A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung

Pulmonary arterial hypertension (PAH) is a vascular disease characterized by persistent precapillary pulmonary hypertension (PH), leading to progressive right heart failure and premature death. The pathological mechanisms underlying this condition remain elusive. Analysis of global metabolomics from...

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Detalles Bibliográficos
Autores principales: Zhao, Yidan D., Chu, Lei, Lin, Kathleen, Granton, Elise, Yin, Li, Peng, Jenny, Hsin, Michael, Wu, Licun, Yu, Amy, Waddell, Thomas, Keshavjee, Shaf, Granton, John, de Perrot, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552732/
https://www.ncbi.nlm.nih.gov/pubmed/26317340
http://dx.doi.org/10.1371/journal.pone.0134958