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A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung
Pulmonary arterial hypertension (PAH) is a vascular disease characterized by persistent precapillary pulmonary hypertension (PH), leading to progressive right heart failure and premature death. The pathological mechanisms underlying this condition remain elusive. Analysis of global metabolomics from...
Autores principales: | Zhao, Yidan D., Chu, Lei, Lin, Kathleen, Granton, Elise, Yin, Li, Peng, Jenny, Hsin, Michael, Wu, Licun, Yu, Amy, Waddell, Thomas, Keshavjee, Shaf, Granton, John, de Perrot, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552732/ https://www.ncbi.nlm.nih.gov/pubmed/26317340 http://dx.doi.org/10.1371/journal.pone.0134958 |
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