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14-3-3 Proteins Buffer Intracellular Calcium Sensing Receptors to Constrain Signaling
Calcium sensing receptors (CaSR) interact with 14-3-3 binding proteins at a carboxyl terminal arginine-rich motif. Mutations identified in patients with familial hypocalciuric hypercalcemia, autosomal dominant hypocalcemia, pancreatitis or idiopathic epilepsy support the functional importance of thi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552738/ https://www.ncbi.nlm.nih.gov/pubmed/26317416 http://dx.doi.org/10.1371/journal.pone.0136702 |