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14-3-3 Proteins Buffer Intracellular Calcium Sensing Receptors to Constrain Signaling

Calcium sensing receptors (CaSR) interact with 14-3-3 binding proteins at a carboxyl terminal arginine-rich motif. Mutations identified in patients with familial hypocalciuric hypercalcemia, autosomal dominant hypocalcemia, pancreatitis or idiopathic epilepsy support the functional importance of thi...

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Detalles Bibliográficos
Autores principales: Grant, Michael P., Cavanaugh, Alice, Breitwieser, Gerda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552738/
https://www.ncbi.nlm.nih.gov/pubmed/26317416
http://dx.doi.org/10.1371/journal.pone.0136702

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