Cargando…
Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity
Chagas disease is one of the most neglected tropical diseases in the world, affecting nearly 15 million people, primarily in Latin America. Only two drugs are used for the treatment of this disease, nifurtimox and benznidazole. These drugs have limited efficacy and frequently induce adverse effects,...
Autores principales: | Cortes, Leonel A., Castro, Lorena, Pesce, Bárbara, Maya, Juan D., Ferreira, Jorge, Castro-Castillo, Vicente, Parra, Eduardo, Jara, José A., López-Muñoz, Rodrigo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552745/ https://www.ncbi.nlm.nih.gov/pubmed/26317199 http://dx.doi.org/10.1371/journal.pone.0136852 |
Ejemplares similares
-
Novel Solid Dispersions of Naphthoquinone Using Different Polymers for Improvement of Antichagasic Activity
por: da Silva Oliveira, Verônica, et al.
Publicado: (2020) -
Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing
por: Bellera, Carolina L., et al.
Publicado: (2014) -
(Furfurylamino)triphenylphosphonium bromide
por: Martínez de León, Carla, et al.
Publicado: (2012) -
Library of Selenocyanate and Diselenide Derivatives as In Vivo Antichagasic Compounds Targeting Trypanosoma cruzi Mitochondrion
por: Martín-Escolano, Rubén, et al.
Publicado: (2021) -
Up-regulation of ATP-binding cassette transporters in the THP-1 human
macrophage cell line by the antichagasic benznidazole
por: Perdomo, Virginia G, et al.
Publicado: (2016)