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Conformational Properties of Seven Toac-Labeled Angiotensin I Analogues Correlate with Their Muscle Contraction Activity and Their Ability to Act as ACE Substrates

Conformational properties of the angiotensin II precursor, angiotensin I (AngI) and analogues containing the paramagnetic amino acid TOAC (2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid) at positions 0, 1, 3, 5, 8, 9, and 10, were examined by EPR, CD, and fluorescence. The conformati...

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Detalles Bibliográficos
Autores principales:	Teixeira, Luis Gustavo D., Malavolta, Luciana, Bersanetti, Patrícia A., Schreier, Shirley, Carmona, Adriana K., Nakaie, Clovis R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552746/ https://www.ncbi.nlm.nih.gov/pubmed/26317625 http://dx.doi.org/10.1371/journal.pone.0136608

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