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Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos

Cell-mediated immunity is essential in protection against rickettsial illnesses, but the role of neutrophils in these intracellular vasculotropic infections remains unclear. This study analyzed the plasma levels of nucleosomes, FSAP-activation (nucleosome-releasing factor), and neutrophil activation...

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Detalles Bibliográficos
Autores principales: Paris, Daniel H., Stephan, Femke, Bulder, Ingrid, Wouters, Diana, van der Poll, Tom, Newton, Paul N., Day, Nicholas P. J., Zeerleder, Sacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552835/
https://www.ncbi.nlm.nih.gov/pubmed/26317419
http://dx.doi.org/10.1371/journal.pntd.0003990