Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets

An important goal of cancer genomic research is to identify the driving pathways underlying disease mechanisms and the heterogeneity of cancers. It is well known that somatic genome alterations (SGAs) affecting the genes that encode the proteins within a common signaling pathway exhibit mutual exclu...

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Detalles Bibliográficos
Autores principales: Lu, Songjian, Lu, Kevin N., Cheng, Shi-Yuan, Hu, Bo, Ma, Xiaojun, Nystrom, Nicholas, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552843/
https://www.ncbi.nlm.nih.gov/pubmed/26317392
http://dx.doi.org/10.1371/journal.pcbi.1004257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552843/
https://www.ncbi.nlm.nih.gov/pubmed/26317392
http://dx.doi.org/10.1371/journal.pcbi.1004257

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