Differential DNA methylation and expression of inflammatory and zinc transporter genes defines subgroups of osteoarthritic hip patients

OBJECTIVES: We have previously shown that the cartilage DNA methylome delineates two clusters of osteoarthritic (OA) hip patients, characterised by differential methylation of inflammatory genes, while others have demonstrated a link between zinc homeostasis and inflammation in OA. We aimed to inves...

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Detalles Bibliográficos
Autores principales: Rushton, Michael D, Young, David A, Loughlin, John, Reynard, Louise N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552898/
https://www.ncbi.nlm.nih.gov/pubmed/25854584
http://dx.doi.org/10.1136/annrheumdis-2014-206752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552898/
https://www.ncbi.nlm.nih.gov/pubmed/25854584
http://dx.doi.org/10.1136/annrheumdis-2014-206752

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