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Modulation of Innate Immune Signalling by Lipid-Mediated MAVS Transmembrane Domain Oligomerization

RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mitochondrial membrane protein MAVS to induce innate immunity to viral infection through type I interferon production. Mitochondrial reactive oxygen species (mROS) have been shown to enhance anti-viral M...

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Detalles Bibliográficos
Autores principales:	Nobre, Luis, Wise, Daniel, Ron, David, Volmer, Romain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552940/ https://www.ncbi.nlm.nih.gov/pubmed/26317833 http://dx.doi.org/10.1371/journal.pone.0136883

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