Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo

TCR-dependent and costimulation signaling, cell division, and cytokine environment are major factors driving cytokines expression induced by CD4+ T cell activation. PEA-15 15 (Protein Enriched in Astrocyte / 15kDa) is an adaptor protein that regulates death receptor-induced apoptosis and proliferati...

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Detalles Bibliográficos
Autores principales: Kerbrat, Stéphane, Vingert, Benoit, Junier, Marie-Pierre, Castellano, Flavia, Renault-Mihara, François, Dos Reis Tavares, Silvina, Surenaud, Mathieu, Noizat-Pirenne, France, Boczkowski, Jorge, Guellaën, Georges, Chneiweiss, Hervé, Le Gouvello, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552951/
https://www.ncbi.nlm.nih.gov/pubmed/26317969
http://dx.doi.org/10.1371/journal.pone.0136885

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