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Effects of Nano-particles on Histo-pathological changes of the fish

Regarding fast development of the nanotechnology and the probably of it’s side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-st...

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Autores principales: Monfared, Ali Louei, Bahrami, Ali Mohammad, Hosseini, Ehsan, Soltani, Salman, Shaddel, Minoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552984/
https://www.ncbi.nlm.nih.gov/pubmed/26322234
http://dx.doi.org/10.1186/s40201-015-0216-9
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author Monfared, Ali Louei
Bahrami, Ali Mohammad
Hosseini, Ehsan
Soltani, Salman
Shaddel, Minoo
author_facet Monfared, Ali Louei
Bahrami, Ali Mohammad
Hosseini, Ehsan
Soltani, Salman
Shaddel, Minoo
author_sort Monfared, Ali Louei
collection PubMed
description Regarding fast development of the nanotechnology and the probably of it’s side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-step reduction process in an aqueous solution. 60 O. mykiss were obtained from a local commercial hatchery. Fish were divided randomly into four groups. Control group was kept in dechlorinated tap water without any add-on material. Experimental groups were exposed to concentration of 3, 300 and 1000 mg/L of nanosilver solution for eight weeks, respectively. Biochemical analyses of sera, histological alterations of the gill and kidney tissue were done. Aneurism in the secondary lamellae and hyperplasia of epithelium in gills, adhesion of the gill lamellae, inducing hyaline cast formation, significant decreasing in the glomerular diameter and formation of intra cytoplasmic vacuoles in the various urinary tubules were seen in experimental groups. The serum levels of total protein was decreased significantly (P < 0.05) by increasing nanosilver concentration but ALP, LDH, AST and ALT increased significantly (P < 0.05). It is concluded that nanosilver induces gill and kidney damages and changes the biochemical parameters of O. mykiss juveniles in different concentrations.
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spelling pubmed-45529842015-08-30 Effects of Nano-particles on Histo-pathological changes of the fish Monfared, Ali Louei Bahrami, Ali Mohammad Hosseini, Ehsan Soltani, Salman Shaddel, Minoo J Environ Health Sci Eng Research Article Regarding fast development of the nanotechnology and the probably of it’s side effects on aquatic body organs, this study investigate the effects of nanosilver administration on histology of gill, kidney and biochemical parameters in common carp. The silver nanoparticles were synthesized in a one-step reduction process in an aqueous solution. 60 O. mykiss were obtained from a local commercial hatchery. Fish were divided randomly into four groups. Control group was kept in dechlorinated tap water without any add-on material. Experimental groups were exposed to concentration of 3, 300 and 1000 mg/L of nanosilver solution for eight weeks, respectively. Biochemical analyses of sera, histological alterations of the gill and kidney tissue were done. Aneurism in the secondary lamellae and hyperplasia of epithelium in gills, adhesion of the gill lamellae, inducing hyaline cast formation, significant decreasing in the glomerular diameter and formation of intra cytoplasmic vacuoles in the various urinary tubules were seen in experimental groups. The serum levels of total protein was decreased significantly (P < 0.05) by increasing nanosilver concentration but ALP, LDH, AST and ALT increased significantly (P < 0.05). It is concluded that nanosilver induces gill and kidney damages and changes the biochemical parameters of O. mykiss juveniles in different concentrations. BioMed Central 2015-08-29 /pmc/articles/PMC4552984/ /pubmed/26322234 http://dx.doi.org/10.1186/s40201-015-0216-9 Text en © Monfared et al. 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Monfared, Ali Louei
Bahrami, Ali Mohammad
Hosseini, Ehsan
Soltani, Salman
Shaddel, Minoo
Effects of Nano-particles on Histo-pathological changes of the fish
title Effects of Nano-particles on Histo-pathological changes of the fish
title_full Effects of Nano-particles on Histo-pathological changes of the fish
title_fullStr Effects of Nano-particles on Histo-pathological changes of the fish
title_full_unstemmed Effects of Nano-particles on Histo-pathological changes of the fish
title_short Effects of Nano-particles on Histo-pathological changes of the fish
title_sort effects of nano-particles on histo-pathological changes of the fish
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552984/
https://www.ncbi.nlm.nih.gov/pubmed/26322234
http://dx.doi.org/10.1186/s40201-015-0216-9
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