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Predicting the spatial organization of chromosomes using epigenetic data
Chromosome folding can reinforce the demarcation between euchromatin and heterochromatin. Two new studies show how epigenetic data, including DNA methylation, can accurately predict chromosome folding in three dimensions. Such computational approaches reinforce the idea of a linkage between epigenet...
Autores principales: | Mourad, Raphaël, Cuvier, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552987/ https://www.ncbi.nlm.nih.gov/pubmed/26319942 http://dx.doi.org/10.1186/s13059-015-0752-8 |
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