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Anti-proliferative Activity of T-bet

T-bet is a critical transcription factor that regulates differentiation of Th1 cells from CD4(+) precursor cells. Since T-bet directly binds to the promoter of the IFN-γ gene and activates its transcription, T-bet deficiency impairs IFN-γ production in Th1 cells. Interestingly, T-bet-deficient Th ce...

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Detalles Bibliográficos
Autores principales:	Oh, Yeon Ji, Shin, Ji Hyun, Won, Hee Yeon, Hwang, Eun Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Association of Immunologists 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553258/ https://www.ncbi.nlm.nih.gov/pubmed/26330806 http://dx.doi.org/10.4110/in.2015.15.4.199

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