Extracellular RNAs: development as biomarkers of human disease

Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cer...

Descripción completa

Detalles Bibliográficos
Autores principales: Quinn, Joseph F., Patel, Tushar, Wong, David, Das, Saumya, Freedman, Jane E., Laurent, Louise C., Carter, Bob S., Hochberg, Fred, Keuren-Jensen, Kendall Van, Huentelman, Matt, Spetzler, Robert, Kalani, M. Yashar S., Arango, Jorge, Adelson, P. David, Weiner, Howard L., Gandhi, Roopali, Goilav, Beatrice, Putterman, Chaim, Saugstad, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Special Issue: Extracellular RNA Communication Consortium
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553262/
https://www.ncbi.nlm.nih.gov/pubmed/26320940
http://dx.doi.org/10.3402/jev.v4.27495
Descripción
Sumario:Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, examine diverse extracellular body fluids, including plasma, serum, urine and cerebrospinal fluid. The disorders studied include hepatic and gastric cancer, cardiovascular disease, chronic kidney disease, neurodegenerative disease, brain tumours, intracranial haemorrhage, multiple sclerosis and placental disorders. Progress to date and the plans for future studies are outlined.

Ejemplares similares