Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice

Glucagon like peptide-1 (GLP-1) receptor agonists such as exendin-4 have been widely used but their short half-life limits their therapeutic value. The recombinant protein, E2HSA, is a novel, long-acting GLP-1 receptor agonist generated by the fusion of exendin-4 with human serum albumin. In mouse p...

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Detalles Bibliográficos
Autores principales: Hou, Shaocong, Li, Caina, Huan, Yi, Liu, Shuainan, Liu, Quan, Sun, Sujuan, Jiang, Qian, Jia, Chunming, Shen, Zhufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553314/
https://www.ncbi.nlm.nih.gov/pubmed/26351642
http://dx.doi.org/10.1155/2015/817839

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