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Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization

Background. Congenital and developmental cataracts are leading causes of childhood blindness and severe visual impairment. They may be associated with systemic diseases including congenital heart diseases which are among the major causes of morbidity and mortality in childhood. The pattern of system...

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Autores principales: Duke, Roseline, Oparah, Sidney, Adio, Adedayo, Eyo, Okon, Odey, Friday
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553323/
https://www.ncbi.nlm.nih.gov/pubmed/26351577
http://dx.doi.org/10.1155/2015/927840
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author Duke, Roseline
Oparah, Sidney
Adio, Adedayo
Eyo, Okon
Odey, Friday
author_facet Duke, Roseline
Oparah, Sidney
Adio, Adedayo
Eyo, Okon
Odey, Friday
author_sort Duke, Roseline
collection PubMed
description Background. Congenital and developmental cataracts are leading causes of childhood blindness and severe visual impairment. They may be associated with systemic diseases including congenital heart diseases which are among the major causes of morbidity and mortality in childhood. The pattern of systemic comorbidities seen in children diagnosed with cataract in Calabar, Nigeria, was studied. Methods. A retrospective review was conducted on the children who had cataract surgery between 2011 and 2012. Diagnosis of the systemic condition was documented. Results. A total of 66 children were recruited for the study. Cardiac disease was seen in 26 children (39.9%), followed by delayed milestone in 16 (24.2%), intellectual disability in 14 (21.2%), deafness in 11 (16.7%), epilepsy in 4 (6.1%), and physical handicap in 3 (4.5%) of them. Clinically confirmed Congenital Rubella Syndrome was seen in 30 (45%) of the children. The pattern of CHD seen was as follows: patent ductus arteriosus in 16 (24.2%) followed by ventricular-septal defect in 5 (7.6%), atrial-septal defect in 3 (4.5%), and pulmonary stenosis in 2 (3%). Conclusion. Systemic comorbidities, especially cardiac anomalies, are common among children with cataract in Nigeria. Congenital Rubella Syndrome may be a prominent cause of childhood cataract in our environment. Routine immunization of school girls against rubella is advocated as a measure to mitigate this trend.
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spelling pubmed-45533232015-09-08 Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization Duke, Roseline Oparah, Sidney Adio, Adedayo Eyo, Okon Odey, Friday J Ophthalmol Research Article Background. Congenital and developmental cataracts are leading causes of childhood blindness and severe visual impairment. They may be associated with systemic diseases including congenital heart diseases which are among the major causes of morbidity and mortality in childhood. The pattern of systemic comorbidities seen in children diagnosed with cataract in Calabar, Nigeria, was studied. Methods. A retrospective review was conducted on the children who had cataract surgery between 2011 and 2012. Diagnosis of the systemic condition was documented. Results. A total of 66 children were recruited for the study. Cardiac disease was seen in 26 children (39.9%), followed by delayed milestone in 16 (24.2%), intellectual disability in 14 (21.2%), deafness in 11 (16.7%), epilepsy in 4 (6.1%), and physical handicap in 3 (4.5%) of them. Clinically confirmed Congenital Rubella Syndrome was seen in 30 (45%) of the children. The pattern of CHD seen was as follows: patent ductus arteriosus in 16 (24.2%) followed by ventricular-septal defect in 5 (7.6%), atrial-septal defect in 3 (4.5%), and pulmonary stenosis in 2 (3%). Conclusion. Systemic comorbidities, especially cardiac anomalies, are common among children with cataract in Nigeria. Congenital Rubella Syndrome may be a prominent cause of childhood cataract in our environment. Routine immunization of school girls against rubella is advocated as a measure to mitigate this trend. Hindawi Publishing Corporation 2015 2015-08-17 /pmc/articles/PMC4553323/ /pubmed/26351577 http://dx.doi.org/10.1155/2015/927840 Text en Copyright © 2015 Roseline Duke et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Duke, Roseline
Oparah, Sidney
Adio, Adedayo
Eyo, Okon
Odey, Friday
Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
title Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
title_full Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
title_fullStr Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
title_full_unstemmed Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
title_short Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
title_sort systemic comorbidity in children with cataracts in nigeria: advocacy for rubella immunization
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553323/
https://www.ncbi.nlm.nih.gov/pubmed/26351577
http://dx.doi.org/10.1155/2015/927840
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