Cargando…

Trichostatin A Modulates Angiotensin II-induced Vasoconstriction and Blood Pressure Via Inhibition of p66shc Activation

Histone deacetylase (HDAC) has been recognized as a potentially useful therapeutic target for cardiovascular disorders. However, the effect of the HDAC inhibitor, trichostatin A (TSA), on vasoreactivity and hypertension remains unknown. We performed aortic coarctation at the inter-renal level in rat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Gun, Lee, Yu Ran, Joo, Hee Kyoung, Park, Myoung Soo, Kim, Cuk-Seong, Choi, Sunga, Jeon, Byeong Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553407/ https://www.ncbi.nlm.nih.gov/pubmed/26330760 http://dx.doi.org/10.4196/kjpp.2015.19.5.467

Ejemplares similares

Tat-Mediated p66shc Transduction Decreased Phosphorylation of Endothelial Nitric Oxide Synthase in Endothelial Cells
por: Lee, Sang Ki, et al.
Publicado: (2012)

Protein kinase C beta II upregulates intercellular adhesion molecule-1 via mitochondrial activation in cultured endothelial cells
por: Joo, Hee Kyoung, et al.
Publicado: (2017)

CRIF1 Deficiency Induces p66shc-Mediated Oxidative Stress and Endothelial Activation
por: Nagar, Harsha, et al.
Publicado: (2014)

Secreted APE1/Ref-1 inhibits TNF-α-stimulated endothelial inflammation via thiol-disulfide exchange in TNF receptor
por: Park, Myoung Soo, et al.
Publicado: (2016)

The 18-kDa Translocator Protein Inhibits Vascular Cell Adhesion Molecule-1 Expression via Inhibition of Mitochondrial Reactive Oxygen Species
por: Joo, Hee Kyoung, et al.
Publicado: (2015)

p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis
por: Shin, Hyo Jung, et al.
Publicado: (2020)

APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells
por: Lee, Ki Mo, et al.
Publicado: (2017)

ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1
por: Lee, Yu Ran, et al.
Publicado: (2019)

P66Shc signals to age
por: Trinei, Mirella, et al.
Publicado: (2009)

p66Shc in Cardiovascular Pathology
por: Haslem, Landon, et al.
Publicado: (2022)

Anthocyanin-Rich Extract from Red Chinese Cabbage Alleviates Vascular Inflammation in Endothelial Cells and Apo E(−/−) Mice
por: Joo, Hee Kyoung, et al.
Publicado: (2018)

Ulmus davidiana ethanol extract inhibits monocyte adhesion to tumor necrosis factor-alpha-stimulated endothelial cells
por: Lee, Ki Mo, et al.
Publicado: (2016)

P66SHC and Ageing: ROS and TOR?
por: Pani, Giovambattista
Publicado: (2010)

P66Shc and vascular endothelial function
por: Kumar, Santosh
Publicado: (2019)

Therapeutic positioning of secretory acetylated APE1/Ref-1 requirement for suppression of tumor growth in triple-negative breast cancer in vivo
por: Lee, Yu Ran, et al.
Publicado: (2018)

Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein
por: Choi, Sunga, et al.
Publicado: (2016)

Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy
por: Hirschhäuser, Christine, et al.
Publicado: (2020)

The Role of p66shc in Oxidative Stress and Apoptosis
por: Galimov, E.R.
Publicado: (2010)

p53 and aging: role of p66Shc
por: Migliaccio, Enrica, et al.
Publicado: (2013)

P66Shc expression in diabetic rat retina
por: Zhao, Ming-Hui, et al.
Publicado: (2018)

Role of p66shc in skeletal muscle function
por: Granatiero, Veronica, et al.
Publicado: (2017)

Mechanosensitive Angiotensin II Receptor Signaling in Pressure‐Induced Vasoconstriction
por: Chen, Yen‐Lin, et al.
Publicado: (2022)

Human SHC‐transforming protein 1 and its isoforms p66shc: A novel marker for prediabetes
por: Jelinek, Herbert F, et al.
Publicado: (2021)

p66(Shc) mediates anoikis through RhoA
por: Ma, Zhenyi, et al.
Publicado: (2007)

Sos-mediated activation of rac1 by p66shc
por: Khanday, Firdous A., et al.
Publicado: (2006)

Correction to: P66Shc expression in diabetic rat retina
por: Zhao, Ming-Hui, et al.
Publicado: (2019)

p66Shc Aging Protein in Control of Fibroblasts Cell Fate
por: Suski, Jan M., et al.
Publicado: (2011)

Prooxidant Properties of p66shc Are Mediated by Mitochondria in Human Cells
por: Galimov, Evgeny R., et al.
Publicado: (2014)

Effects of Resveratrol on p66Shc phosphorylation in cultured prostate cells
por: Conte, A., et al.
Publicado: (2016)

p66Shc Signaling Mediates Diabetes-Related Cognitive Decline
por: Minami, Yohei, et al.
Publicado: (2018)

p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy
por: Frackelton, A Raymond, et al.
Publicado: (2006)

P66Shc (Shc1) Zebrafish Mutant Line as a Platform for Testing Decreased Reactive Oxygen Species in Pathology
por: Haslem, Landon, et al.
Publicado: (2022)

JNK/p66Shc/ITCH Signaling Pathway Mediates Angiotensin II-induced Ferritin Degradation and Labile Iron Pool Increase
por: Borkowska, Andżelika, et al.
Publicado: (2020)

Phosphorylation of p66Shc and forkhead proteins mediates Aβ toxicity
por: Smith, Wanli W., et al.
Publicado: (2005)

The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration
por: Savino, Costanza, et al.
Publicado: (2013)

Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc
por: Haller, Martina, et al.
Publicado: (2016)

Lower p66Shc promoter methylation in subjects with chronic renal failure
por: Hamdi, Radhia, et al.
Publicado: (2021)

p66Shc-mediated oxidative stress is involved in gestational diabetes mellitus
por: Huang, Ting-Ting, et al.
Publicado: (2021)

Plasma APE1/Ref-1 Correlates with Atherosclerotic Inflammation in ApoE(−/−) Mice
por: Lee, Yu Ran, et al.
Publicado: (2020)

Altered Secretory Activity of APE1/Ref-1 D148E Variants Identified in Human Patients With Bladder Cancer
por: Lee, Yu Ran, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_thmivhsleshq2maeaboi3o292m