Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins

Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not...

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Detalles Bibliográficos
Autores principales: Bernardo, Travis J., Dubrovsky, Edward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553631/
https://www.ncbi.nlm.nih.gov/pubmed/26467963
http://dx.doi.org/10.3390/insects3010324
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author Bernardo, Travis J.
Dubrovsky, Edward B.
author_facet Bernardo, Travis J.
Dubrovsky, Edward B.
author_sort Bernardo, Travis J.
collection PubMed
description Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH.
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spelling pubmed-45536312015-10-08 Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins Bernardo, Travis J. Dubrovsky, Edward B. Insects Review Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH. MDPI 2012-03-22 /pmc/articles/PMC4553631/ /pubmed/26467963 http://dx.doi.org/10.3390/insects3010324 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Bernardo, Travis J.
Dubrovsky, Edward B.
Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
title Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
title_full Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
title_fullStr Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
title_full_unstemmed Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
title_short Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins
title_sort molecular mechanisms of transcription activation by juvenile hormone: a critical role for bhlh-pas and nuclear receptor proteins
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553631/
https://www.ncbi.nlm.nih.gov/pubmed/26467963
http://dx.doi.org/10.3390/insects3010324
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