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Epigenetic Modifications and Accumulation of DNA Double-Strand Breaks in Oral Lichen Planus Lesions Presenting Poor Response to Therapy
Epigenetics refers to changes in cell characteristics that occur independently of modifications to the deoxyribonucleic acid (DNA) sequence. Alterations mediated by epigenetic mechanisms are important factors in cancer progression. Although an exciting prospect, the identification of early epigeneti...
Autores principales: | Dillenburg, Caroline S., Martins, Marco A.T., Almeida, Luciana O., Meurer, Luise, Squarize, Cristiane H., Martins, Manoela D., Castilho, Rogerio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554108/ https://www.ncbi.nlm.nih.gov/pubmed/26222871 http://dx.doi.org/10.1097/MD.0000000000000997 |
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