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Transcriptome analysis of the mouse E14.5 (TS23) developing humerus and differential expression in muscle-less mutant embryos lacking mechanical stimulation

Mechanical stimulation is important for the correct formation of the skeleton. Splotch-delayed mutant embryos (Pax3(Spd/Spd)) that develop with no limb muscle and therefore no limb movement experience an altered mechanical environment resulting in specific defects in ossification and joint formation...

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Detalles Bibliográficos
Autores principales: Rolfe, Rebecca A., Kenny, Elaine M., Cormican, Paul, Murphy, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554290/
https://www.ncbi.nlm.nih.gov/pubmed/26484063
http://dx.doi.org/10.1016/j.gdata.2014.03.003