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Transcriptome analysis of the mouse E14.5 (TS23) developing humerus and differential expression in muscle-less mutant embryos lacking mechanical stimulation
Mechanical stimulation is important for the correct formation of the skeleton. Splotch-delayed mutant embryos (Pax3(Spd/Spd)) that develop with no limb muscle and therefore no limb movement experience an altered mechanical environment resulting in specific defects in ossification and joint formation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554290/ https://www.ncbi.nlm.nih.gov/pubmed/26484063 http://dx.doi.org/10.1016/j.gdata.2014.03.003 |